UK NEQAS ICC & ISH Modules

Currently laboratories are able to participate in any, or all of our

  • 12 different immmunocytochemistry Modules
  • 3 in-situ hybridisation Modules

Modules chosen will depend on your service scope and areas of special interest.

Module 1
General Pathology

This module offers FOUR assessment runs per year with the assessment of TWO antigens on each run.

Module 2A
Breast Pathology (Hormonal Receptors – ER only)

This module offers FOUR assessment runs per year with the assessment of ER at each run

Module 2B
Breast Pathology (Hormonal Receptors – ER and PR)

This module offers FOUR assessment runs per year with the assessment of both antigen at each run

Module 3
Breast Pathology HER2 IHC

This module offers FOUR assessment runs per year with the assessment of HER2 at each run

Module 4
Lymphoid Pathology

This module offers FOUR assessment runs per year with the assessment of TWO antigens at each run

Module 5
Neuropathology

This module offers FOUR assessment runs per year with the assessment of TWO antigens at each run

Module 6
Cytopathology

This module offers FOUR assessment runs per year with the assessment of TWO antigens at each run on cytospin preparations or cell block sections, distributed by the scheme and on participants in house controls which should preferably consist of cytoloical preparations

Module 7
Alimentary Tract Pathology – GIST

This module offers FOUR assessment runs per year with the assessment of TWO antigens at each run. CD117 is always the Gold and either: DOG-1 or CD34 or Desmin or S100 will be the 2nd antigen

Module 8
Gastric HER2 IHC

This module offers FOUR assessment runs per year on samples of gastric cancer of varying HER2 membrane protein expression.

Module 9
HER2 ISH Interpretive & Technical

This module offers FOUR assessment runs per year on cell lines and tissue samples of varying degrees of HER2 gene status.

Module 10
NSCLC ALK IHC

This module offers FOUR assessment runs per year on cell lines and tissue samples of varying degrees of ALK expression.

Module 11
NSCLC PD-L1 IHC (Pilot)

This module offers FOUR assessment runs per year on cell lines and tissue samples of varying degrees of PD-L1 expression.

Module 12
NSCLC ALK/ROS1 FISH (Pilot)

This module offers FOUR assessment runs per year on cell lines and tissue samples of known ALK and ROS1 gene status.

Module 13
Mismatch Repair (MMR) Proteins

This module offers FOUR assessment runs per year with the assessment of TWO paired antigens at each run. MLH1 & PMS2 OR MSH2 & MSH6 will be requested alternately.

Module 14
NSCLC ROS1 IHC (Pilot)

This module offers FOUR assessment runs per year on cell lines of varying degrees of ROS1 expression.